Webinar Description
The risk assessment process, in relation to human health entails a sequence of actions which is outlined below.
(1) Assessment of effects, comprising
(a) hazard identification: identification of the adverse effects which a substance has an inherent capacity to cause; and
(b) hazard characterisation: dose (concentration) – response (effects) assessment: estimation of the relationship between dose, or level of exposure to a substance, and the incidence and severity of an effect, where appropriate.
(2) Exposure assessment: estimation of the concentrations/doses to which human populations (i.e. workers, consumers and man exposed indirectly via the environment) or environmental compartments (aquatic environment, terrestrial environment and air) are or may be exposed.
(3) Risk characterisation: estimation of the incidence and severity of the adverse effects likely to occur in a human population or environmental compartment due to actual or predicted exposure to a substance, and may include “risk estimation”, i.e. the quantification of that likelihood. Combined exposure to multiple chemicals and dietary risk assessment should also be considered where relevant.
In a quantitative assessment, the risk is characterised by comparing the estimated exposure with a DNEL. This approach is not available in a qualitative assessment, as a DNEL has not been derived. Nevertheless, it may be possible to compare the estimated exposure with a benchmark value to get an indication of whether the exposure is likely to be controlled.
Agenda
- EU Human Health Risk Assessment – basics
- Effects assessment
- Exposure assessment for workers
- Risk characterisation in occupational RA
- Q&A
Who should attend
Companies / experts – interested in the EU human health risk assessment.
Presenter
Martin Murín, Martina Kubáňová, Ekotox experts